Can Cialis Damage Your Heart?

Cialis (Tadalafil) is considered one of the best drugs that are used to enhance potency and treat erectile dysfunction. Like Viagra, it affects the muscles of the penile vessels, increasing blood flow, as a result of which a man becomes able to achieve a high-quality healthy erection. Just one tablet of Cialis is able to support a man’s sexual power for as long as 36 hours.

Blood pressure decrease as a symptom of Cialis effect on the heart

Cialis relaxes the smooth muscles of the arteries, slightly lowering blood pressure. Because of this, low blood pressure or hypotension may become a problem. Hypotension is defined as a decrease in blood pressure. below 90/60 (mmHg). In the most moderate form, low blood pressure makes people vulnerable to fainting, falls and injuries. If the blood pressure drops too low, vital organs may fail, which can lead to death.

In phase III clinical trials of tadalafil, none of the patients (out of 949) had clinical hypotension. In phase III studies evaluating the safety of tadalafil when taken with drugs that lower blood pressure (so-called hypotensive), the combination only slightly increased the risk of low blood pressure. When taking two or more antihypertensive drugs at the same time, tadalafil did not increase the incidence of hypotension.

Another form of low blood pressure is orthostatic hypotension, which is characterized by: a sudden decrease in blood pressure occurs when a person gets up from a sitting or lying position. Orthostatic hypotension, although often harmless, causes only dizziness. it can lead to serious consequences, depending on its cause. In the study (mentioned above) devoted to this problem, it was found that tadalafil does not have a clinically significant effect on orthostatic hypotension.

Who should not take Cialis?

There are certain categories of conditions that should make men avoid taking Cialis:

• hypersensitivity to tadalafil or to any substance that is part of the drug;
• taking drugs containing any organic nitrates;
• the presence of contraindications to sexual activity in patients with diseases of the cardiovascular system: myocardial infarction during the last 90 days, unstable angina, occurrence of angina attack during sexual intercourse, heart failure of classes II-IV according to the classification of the New York Cardiological Association (NYHA), developed during the last 6 months, uncontrolled arrhythmia, arterial hypotension (blood pressure less than 90/50 mmHg), uncontrolled hypertension, ischemic stroke during the last 6 months;
• vision loss due to non-arteritis-related anterior ischemic optic neuropathy (NAPION) (regardless of the connection with the use of PDE5 inhibitors);
• simultaneous administration of doxazosin, as well as medications for the treatment of erectile dysfunction;
• frequent (more than 2 times a week) use in patients with chronic renal insufficiency (less than 30 ml / min);
• hereditary galactose intolerance, Lapp-lactase deficiency and glucose-galactose malabsorption;
• children and adolescence to 18 years.